Some of the league's best hurlers take the mound on Wednesday's 11-game main slate, while the Yankees get yet another chance to beat up the Orioles. The Cubs and Astros also find themselves in juicy matchups as two other teams with implied totals well over five runs.

Our daily helper is available every day to analyze FanDuel's main slate and help give you a starting point when you're building lineups. Be sure to also incorporate our great tools into your research process. Whether you're looking for daily projections, the latest starting lineups and weather, or batting and pitching heat maps to find the best matchups -- we've got you covered! And don't forget to take a listen to The Solo Shot podcast with Jim Sannes, who breaks down the MLB daily fantasy slate each day.

On that note, let's highlight some of the top options for today's FanDuel main slate.

Pitchers to Target

High-Priced Pitchers

Gerrit Cole ($11,700 on FanDuel): Wednesday's most expensive hurler not only leads the league in strikeout rate (38.3%) and SIERA (2.54), but he faces the same team that Justin Verlander annihilated last night (67 FanDuel points). Verlander's 12 strikeouts didn't exactly come out of nowhere against the White Sox, whose active roster carries the fourth-highest strikeout rate versus righties (25.5%), and Cole could very well dominate in similar fashion tonight. After all, with that mighty strikeout rate, he's tallied eight or more punchouts in eight of his 10 starts and reached double-digits five times. Chicago has a middling implied total (3.10), and Cole will also have a fantastic shot at a win, with Houston's offense expected to pummel Ivan Nova.