FanDuel Price: $5,300

And once again, we have a starting running back who is out with an injury. It's LeSean McCoy who is sitting in this case, and it's a low-priced back in Mike Gillislee stepping up into what will likely be a workhorse role.

The Buffalo Bills have been the league's third-most run-heavy team with a 1.02 pass-to-run ratio. McCoy has averaged 17.3 carries and 4.0 targets per game this season. That leaves a ton of opportunity up for grabs, and Gillislee should fill a lot of it.

It helps that Gillislee also has a solid matchup as the Bills are 3-point favorites against a Miami Dolphins team that ranks 27th in Adjusted Defensive Rushing NEP per play.