Ryan Mathews is questionable for Week 12 and dealing with a sprained MCL, and while Darren Sproles is expected to play, he is dealing with a fractured rib. This creates a void in the Philadelphia Eagles backfield, leaving room for Wendell Smallwood.

Smallwood led Eagles running backs by playing 48% of the team's offensive snaps in Week 11 and has 13 carries in each of his last two games. He also saw five targets in the passing game last week.

The Green Bay Packers' run defense ranks well, and while their early-season success makes them look like they aren't a good team to target running backs against, they have allowed 20-plus fantasy points to starting running backs in four straight games.