High-Cost Option: New England Patriots ($3,700)
Rookie Jared Goff and the Los Angeles Rams travel east to take on the Danny Woodhead-led New England Patriots in Foxborough. Bill Belichick should find ways to disrupt Goff and the Rams' offense. The Patriots are currently 13-point favorites and should force Goff to throw often. The Rams have allowed the 10th-most sacks, and Goff already has two turnovers and four sacks in his first two games.
Mid-Cost Option: Green Bay Packers ($2,900)
Brock Osweiler hoodwinked the Houston Texans into a boatload of money this offseason and has really hampered Bill O'Brien's offense. Osweiler has thrown 13 interceptions and has 5 fumbles this season. Houston has also allowed the 10th-most quarterback hits this season. Pressures, sacks, and turnovers are what we should be targeting here, and the Packers are in a nice spot to capitalize on all three.
Low-Cost Option: San Diego Chargers ($2,900)
It's probably best to pay up for the Patriots defense or the Denver Broncos -- who face Blake Bortles -- this week with most of the lower-priced defenses in less-than-ideal spots. The San Diego Chargers are probably best suited for tourneys, but there is some upside here. Jameis Winston will be traveling west to San Diego to take on a defense that leads the league in interceptions and has the second-most turnovers forced this season. The Chargers' pass-rush productivity between Melvin Ingram and Joey Bosa gives them a chance to pressure Jameis Winston, who has thrown 11 picks this year in 11 games.
Other Options: Denver Broncos ($3,900)