| Player | Pos | Games | CarAV |
|---|---|---|---|
| Peyton Manning | QB | 266 | 177 |
| Reggie Wayne | WR | 211 | 117 |
| Alan Faneca | G | 206 | 114 |
| Eli Manning | QB | 201 | 109 |
| Ed Reed | DB | 174 | 106 |
| Warrick Dunn | RB | 181 | 95 |
| Andrew Whitworth | T | 168 | 84 |
| Matt Forte | RB | 134 | 78 |
| Vincent Jackson | WR | 155 | 76 |
| Todd McClure | C | 198 | 74 |