1960 to Present
| Player | Position | Career AV | Games |
|---|---|---|---|
| Bruce Smith | DE | 196 | 217 |
| Thurman Thomas | RB | 136 | 173 |
| Jim Kelly | QB | 132 | 160 |
| Andre Reed | WR | 132 | 221 |
| Kent Hull | C | 107 | 170 |
| O.J. Simpson | RB | 107 | 112 |
| Joe Ferguson | QB | 100 | 164 |
| Fred Smerlas | DT | 97 | 162 |
| Mike Stratton | LB | 95 | 142 |
| Jim Ritcher | G | 88 | 203 |