Price: $5,700

The Giants' running game isn't the only thing that gains appeal from this matchup with the 49ers. San Francisco also ranks 24th in Adjusted Defensive Passing NEP per play, allowing above-average fantasy production to opposing wide receivers.

Since New York is dealing with a severely depleted wide receiving corps, Sterling Shepard will serve as their top wideout, all but locking him in to big volume the rest of the way.

He saw nine targets in Week 9, turning that into 5 receptions and 70 yards despite dealing with a much tougher matchup against a Los Angeles Rams team that ranks top-10 against the pass.

Shepard's salary isn't likely to stay this low for long, as his production will pick up with that significant volume. He's very underpriced relative to the kind of damage that he can do to a struggling 49ers secondary.