While the duo of Giovani Bernard and Jeremy Hill didn't gash the Patriots like the Chiefs did in Week 4, there's no reason to overthink their potential in Week 6.
The Panthers don't have too fearsome a defense, particularly against the running back, and they allowed four rushing touchdowns in their past three games.
The Bengals nearly cut their rushing attempts in half against the Patriots in Week 5. They ran the ball only 18 times but averaged 34.0 carries in their first 3 games.
A steady dose of rushing against the porous Panthers defense should give Hill enough chances to post a useful fantasy day for you as a flex option.