This is a bit of a zigging-while-others-are-zagging recommendation, but Rueben Randle led Giants receivers in targets with 10.
Even though Odell Beckham (9 targets) and Preston Parker (7) ended up with bigger stat lines than Randle's 5 for 39, there's still reason to believe he is a safe bet for targets moving forward.
The 49ers are a bottom-half defense in fantasy points allowed to receivers despite playing the non-threatening wideouts from Kansas City and St. Louis (twice) in three of their past five games. Randle could be a sneaky start in a positive matchup while Beckham starts shifting attention his way.