The Week 5 slate has a few high-scoring games that you should get some exposure in, with the New England Patriots at the Dallas Cowboys paving the way with a 49.5-point total over/under. The Falcons, Chiefs, Packers, and Giants are all at least 7-point home favorites. With only 4 of the 15 games expected to be within three points per Vegas spreads, this could be another week with a ton of points at the running back position as several blowouts are projected.

As a rule of thumb, you want your players to hit three times their value; that is to say for each $1,000 in salary, we want that player to achieve three fantasy points (i.e. If customizable lineups by inputting your players and seeing what our projections offer for the week. There's even an optimization function that'll use our algorithms to help fill out the rest of your daily lineup and give you the best chance of succeeding on game day.

Using Vegas spreads and totals, our Net Expected Points (NEP) metric, and some daily fantasy gamesmanship, we'll take a look at which players you should target this weekend.

As a reminder, the Carolina Panthers, Miami Dolphins, Minnesota Vikings, and New York Jets will all be on their bye weeks.