Week 6 comes in hot and heavy, with Vegas projecting four games on the slate to exceed 50 or more points. It could get crazy.

Remember, as a rule of thumb in daily fantasy, you want your players to hit three times their value; that is to say for each $1,000 in salary, we want that player to achieve three fantasy points (If customizable lineups by inputting your players and seeing what our projections offer for the week. There's even an optimization function that'll use our algorithms to help fill out the rest of your daily lineup and give you the best chance of succeeding on game day.

Using Vegas spreads and totals, our Net Expected Points (NEP) metric, and some daily fantasy gamesmanship, let's take a look at which players you should target this weekend.

As a reminder, the Dallas Cowboys, Oakland Raiders, St. Louis Rams, and Tampa Bay Buccaneers will all be on their bye weeks.