It's been well publicized that the Oakland Raiders struggle against the tight end, but the New York Giants are a close second in points allowed to the tight end position (12.3 per game) this season.
Austin Seferian-Jenkinsis scheduled to return from a multi-week absence and looks primed for a good game against the vulnerable Giants secondary. With Vincent Jackson expected to be out a few more weeks and Louis Murphy out for the season, Seferian-Jenkins would be the second receiving option in this suddenly functional passing game if he's able to suit up.
Ranking 25th against the pass, in terms of Adjusted Defensive Passing NEP per play, the Giants should struggle to stop Mike Evans and Seferian-Jenkins if Winston can manage to limit his mistakes.
Keep an eye on the injury report before locking Seferian-Jenkins into your lineups though. While he's expected to play at this point, things can change as the week progresses.