San Francisco 49ers running back Christian McCaffrey (ankle) is not practicing on Wednesday.
McCaffrey is dealing with a mild ankle sprain ahead of Sunday's Week 18 game against the Arizona Cardinals, but the 49ers are likely just holding him out Wednesday to be safe. If the ankle issue winds up being a more serious problem, Jordan Mason and Tyrion Davis-Price will likely split backfield duties on Sunday. Elijah Mitchell (knee) might also be available after the 49ers designated him to return from injured reserve on Wednesday.
numberFire's models project CMC for 22.2 FanDuel points in Week 18, with 20.6 carries and 4.7 receptions for 134.4 yards of offense. He's the top running back and No. 3 overall player in our fantasy rankings for the final week of the regular season.
Source: David Lombardi, The Athletic