As mentioned in the opening, the odds favor one team heavily in most of these matches. There may be some DFS players that attempt to go full contrarian, but that is unlikely to pay off.

That means paying up for some players on good teams, but a closer look at the odds shows why that will be vital. Arsenal's 2/5 odds imply a 71.4% win chance. Manchester City is at 1/12, which is over a 90% win probability. Tottenham are sitting at a 71.4% win probability. Even Wolves and Everton are close to 60% implied win odds.

These odds also mean that players like Sergio Aguero ($12,500), Raheem Sterling ($11,000), Son Heung-min ($8,000), and Raul Jimenez ($9,000) all have at least a 20% chance of scoring on the day. Those are among the best odds on the entire slate. FanDuel has always rewarded goals and they are currently worth 15 points a piece, so take advantage.