The Miami D/ST is likely to be a popular defensive streamer this week -- and for good reason. Only the Cleveland Browns would have the misfortune of losing their top two quarterbacks to injury in the first two weeks of the season.

Now, Cody Kessler is expected to step in and make his first NFL start on the road against the Dolphins, and the Browns also lost their prized rookie wideout Corey Coleman to a broken hand in practice on Wednesday for an uncertain amount of time.

Aside from the common sense part of playing a defense at home versus a rookie, there are some trends worth mentioning.

Pinnacle Sports opened the spread at -7 for the Dolphins. Since the announcement of the Josh McCown injury, the spread has climbed to -9.5 for Miami, making them the largest favorite of the weekend along with the Seattle Seahawks.

The total for this game is the low amount of 42 points. The implied total for the Browns is only 16.25 points.

The Dolphins are the seventh-most expensive defense on Fanduel at $4,600. They have the upside of a top-five defense and are priced outside of it, making them a solid play in all formats.